This episode explores recent updates in fertility research, focusing on anti-Müllerian hormone (AMH) and its relationship with PCOS and vitamin D, as well as the influence of weekly and lunar rhythms on the menstrual cycle. Against this backdrop, Dr. Natalie Crawford, a board-certified OB-GYN and fertility physician, shares her personal journey into reproductive medicine, highlighting the importance of research and dedication in her career path. More significantly, the episode delves into a study revealing that higher AMH levels in women with PCOS correlate with lower ovulation rates when using clomiphene and metformin. For instance, each unit increase in AMH decreased ovulation odds by 10%. Another study showed a positive association between vitamin D levels and AMH, suggesting that vitamin D deficiency might negatively impact fertility. Finally, a large-scale study indicated a seven-day rhythmicity in menstrual cycles, peaking on Thursdays and Fridays, with a subtle interaction with the lunar cycle. What this means for patients is a better understanding of factors influencing fertility and the potential for personalized treatment strategies.
