This Huberman Lab podcast episode focuses on nicotine's effects on the brain and body, distinguishing nicotine itself from its various delivery methods (smoking, vaping, etc.). The episode details nicotine's impact on dopamine, acetylcholine, and norepinephrine, explaining its effects on mood, focus, and metabolism. It highlights the dangers of smoking and vaping, emphasizing the significantly increased risk of various health problems and reduced lifespan. The podcast also explores methods for quitting nicotine use, including hypnosis (via the Reverie app) and pharmacologic approaches like bupropion, suggesting a combination of nicotine replacement therapies for optimal results. Finally, it stresses the importance of addressing nicotine addiction due to its powerful effects on the brain's reward system.
