Bacteriophages

In this episode of "In Our Time," Martha Clokie leads a discussion with James Ebdon and Claas Kirchhelle about bacteriophages (or phages), viruses that infect and kill bacteria. The conversation traces the discovery of phages, their role in understanding bacterial genetics, and their potential to combat antibiotic resistance. The speakers explore the history of phage research, including key figures like Félix Derelle and George Eliava, and discuss the impact of antibiotics on phage research. They delve into the life cycle of phages, their abundance in various environments, and their potential applications in diagnostics, water quality monitoring, and therapeutics, while also addressing the challenges of developing phage treatments and the need for careful regulation to avoid overuse and ecological impacts. The episode concludes with an optimistic outlook on the future of phage research, emphasizing the importance of interdisciplinary collaboration and responsible development.