This is an interview podcast where host Anthony Pompliano speaks with Dave Collum, a Cornell University chemistry professor, about Collum's annual "Year in Review" document. The conversation covers a wide range of topics including stock market valuations, the Federal Reserve's impact on the economy, the potential for a market crash, the merits of price gouging, cancel culture, and the upcoming Trump administration. Collum expresses skepticism about current market valuations, suggesting they are significantly overvalued and predicting a potential 70% drop. Pomp and Collum discuss the implications of various political and economic factors, including the potential impact of onshoring manufacturing and the role of prediction markets. Listeners gain insights into diverse perspectives on current events and economic trends, prompting critical thinking about the future of markets and politics.