This Huberman Lab Essentials episode is a monologue podcast focusing on the science of stress and its relationship to emotions. The podcast begins by defining stress as a generalized system that mobilizes the body, then explains the acute stress response, detailing the release of adrenaline and its effects on various bodily functions. It introduces the "physiological sigh," a breathing technique involving a double inhale followed by a long exhale, as a tool to quickly reduce stress by regulating heart rate. The episode further categorizes stress into short-term (beneficial for immune function), medium-term (requiring stress threshold elevation), and long-term (detrimental to health), offering specific techniques for managing each. Listeners gain practical tools like breathing exercises and strategies for managing stress across different timescales, ultimately aiming to improve emotional regulation and overall well-being.