#333 ‒ Longevity roundtable — the science of aging, geroprotective molecules, lifestyle interventions, challenges in research, and more | Steven Austad, Matt Kaeberlein, Richard Miller
This panel discussion podcast, featuring Peter Attia and three experts in geroscience (Drs. Steve Austad, Richard Miller, and Matt Kaeberlein), explores the burgeoning public interest in longevity science. The conversation covers the often-confusing relationship between healthspan and lifespan, examining whether extending one necessarily extends the other, and delves into the challenges of evaluating longevity interventions in humans. Specific interventions like rapamycin and senolytics are discussed, along with the limitations of current biomarkers for measuring biological aging. The panelists also debate the role of epigenetic changes and the funding challenges facing longevity research, highlighting the fact that 90% or more of causes of death increase with age, yet receive only a tiny fraction of research funding. The discussion concludes with a call for more research into aging rate indicators and a more integrated approach to studying aging and age-related diseases.
