This Radiolab episode explores instances where the brain malfunctions, causing a disconnect between intention and action. It features an interview with Liza Schoenfeld, a researcher who experienced acute dystonia—a side effect of medication—that mimicked the effects of her lab's experiments on mice, temporarily paralyzing her facial muscles and neck. The episode also recounts Rosemary Morton's experience with labyrinthitis, a condition causing intense vertigo and a distorted sense of space, highlighting the mysterious nature of some neurological conditions. Both stories illustrate the unpredictable nature of the brain and the sometimes-unexplained disruptions to bodily functions. The episode concludes with staff credits and sponsor announcements.