This podcast episode features Peter Attia interviewing Dr. Mike Israetel, a PhD in sports physiology, about resistance training. The conversation covers Dr. Israetel's background, the principles of resistance training (exercise selection, volume, intensity, frequency), debunking myths about accidental muscle growth, and creating effective training routines for various experience levels. Dr. Israetel also candidly discusses his personal experience with anabolic steroids, highlighting both the significant muscle growth and potential long-term health risks. Listeners gain practical advice on optimizing resistance training for muscle growth and an understanding of the dedication required to build significant muscle mass, even with anabolic steroid use. The episode concludes with a discussion of the role of genetics, age, and lifestyle factors in achieving fitness goals.