This podcast interviews Dr. Chris Palmer, a psychiatrist, about his research on the connection between mental health and metabolic disorders. The discussion begins with Dr. Hyman introducing the gut-brain connection and its role in mental health, followed by Dr. Palmer's explanation of his work focusing on mitochondria and metabolic dysfunction as the root of many mental illnesses. Dr. Palmer highlights the ketogenic diet's effectiveness in rebalancing neurotransmitters and reducing brain inflammation, emphasizing the need for a multifaceted approach to treatment, including diet, exercise, and stress reduction. A key takeaway is the understanding that many mental health issues stem from systemic problems affecting the brain, not solely from psychological factors. The interview concludes with a discussion on the need for more research into comprehensive treatments that address metabolic dysfunction to improve mental health outcomes.