Patrick Collison — Why Silicon Valley's most talented should leave

This podcast episode explores various topics ranging from the advice for people in their 20s and whether they should go to San Francisco, to the limitations of the current academic research structure in biomedical science, the constancy of US GDP growth, the potential of CRISPR technology in understanding cellular processes, the threats and potential of biology, the impact of Fast Grants, the concept of autonomous transactions and the potential role of cryptocurrencies, the importance of API design and multi-decadal thinking in technology, the significance of tax law changes in the online context, the challenges and importance of maintaining reliability while deploying software quickly, the importance of taking goals seriously in achieving growth, and the perception of big businesses, startups, and small businesses.