This episode explores the intersection of neuroimaging (like MRI, CT, and PET scans) and machine learning in medical diagnosis and treatment. Against the backdrop of the historical development of neuroimaging techniques, the discussion highlights the increasing volume of data requiring more efficient analysis methods. More significantly, the conversation delves into how machine learning, particularly convolutional neural networks and support vector machines, is being applied to classify scans, identify affected brain regions (for instance, in epilepsy), and predict treatment outcomes. However, challenges remain, including limited data availability and the need for explainable AI to build trust among medical professionals. Despite these hurdles, the potential for AI to augment, not replace, the work of radiologists and neurologists is emphasized, with a vision of AI-powered systems prioritizing scans, generating preliminary reports, and facilitating faster, more accurate diagnoses. This signifies a crucial shift towards a collaborative human-AI approach in neuroimaging, improving efficiency and potentially leading to earlier and more effective interventions.