GPT-5 comes alive, Apple is struggling, and Ripple bought Rail | E2162

In this episode of "This Week in Startups," Jason Calacanis and Lon Harris discuss a range of topics, starting with their disappointment in Apple's lack of innovation under Tim Cook and debating whether he should step down, followed by a discussion on the launch of ChatGPT-5 and its implications for coding and AI applications, with a comparison to other AI models like Claude. They also analyze Ripple's acquisition of Rail and the evolving regulatory landscape for stablecoins, and the potential risks of allowing crypto and private equity investments in 401(k)s. The conversation shifts to Truth Social's AI chatbot powered by Perplexity and the dangers of biased AI, and the ethical concerns surrounding AI therapy, leading to a discussion on state versus federal regulation of AI. Finally, they touch on Anthropic's revenue growth, the total addressable market for language models, and earnings reports from DoorDash and Airbnb, highlighting trends in the tech and investment sectors.