Dr. Elizabeth Mack interviews Dr. Anil Sachdev about his article on transpulmonary pressure-guided mechanical ventilation for severe acute respiratory distress syndrome in the PICU, a retrospective study from North India. Dr. Sachdev discusses the origins of the study, the equipment used, and the challenges of conducting research in a developing country, including the cost considerations for families. He explains the esophageal pressure monitoring research protocol, the availability of the technology, and the criteria for patient selection. Dr. Sachdev shares the study's results, noting the improved oxygenation and ventilation observed with transpulmonary pressure monitoring, and discusses the heterogeneous group of illnesses among the children studied. He also shares insights on catheter insertion techniques for young children and the impact of the COVID-19 pandemic on the study's progress.
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