05 Nov 2025
1h 10m

TECH007: Longevity Roadmap w/ Seb Bunney (Tech Podcast)

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The Investor's Podcast (We Study Billionaires) - The Investor’s Podcast Network

In this episode of Infinite Tech, Preston Pysh and Seb Bunney delve into David Sinclair's book "Lifespan," exploring the science of longevity and health technology. They discuss Ray Kurzweil's prediction of achieving longevity escape velocity by 2032 and unpack Sinclair's core thesis that aging is a disease caused by information loss in epigenetics. The hosts explain complex biological concepts like DNA, epigenetics, Yamanaka factors, sirtuins, and NAD+ in layman's terms, using analogies to make the science accessible. They also touch on practical implications, such as fasting, cold exposure, and the use of NMN supplements, while also considering the broader philosophical questions around extending life and its impact on society.

Outlines

Part 1: Introduction to Longevity

Part 2: Scientific Basis of Aging Reversal

Part 3: Implications and Reflections

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