A synthetic cell that feeds, grows, divides — and happens to look like a potato. This week Sean and Andrew open the summer season with SpudCell, a lab-built cell recently unveiled by Kate Adamala's group at the University of Minnesota and chronicled by Carl Zimmer in the New York Times. Assembled from lifeless chemicals rather than born from a parent cell, it does an unsettling number of the things living cells do, which is exactly why it's so hard to look away from. The conversation isn't really about lipid membranes and plasmids, though. It's about the line — the one we assume exists between the synthetic and the alive, between something that was built and something that is. If a cell metabolizes, replicates, and passes most of the tests we'd give a "real" one, what are we actually measuring when we ask whether it's alive? And once it divides, is the copy still synthetic, or did something cross over? From there the hosts wander happily through the field's shadow archive — Andromeda Strain, The Blob, sea monkeys, pod people — before circling back to the genuinely hopeful: micro-factories that brew medicine on demand, cells that could act as a second immune system, and the slow philosophical creep of the Ship of Theseus applied to your own body. (At what point, exactly, are you "Spud Sean"?) The episode closes with a candid, funny detour into what it feels like when an AI assistant stops deferring and starts correcting you. Part one of a two-part summer set — stay tuned for the watch list.

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Modem Futura is a production of the Future of Being Human initiative at Arizona State University. Be sure to subscribe on Apple Podcasts, Spotify, or wherever you listen to your favorite shows. To learn more about the Future of Being Human initiative and all of our other projects visit - https://futureofbeinghuman.asu.edu

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Host Bios:

Sean M. Leahy, PhD - ASU Bio
Sean is an internationally recognized technologist, futurist, and educator innovating humanistic approaches to emerging technology through a Futures Studies approach. He is the Executive Director for the Future of Being Human Initiative and Research Scientist for the School for the Future of Innovation in Society and Senior Global Futures Scholar with the Julie Ann Wrigley Global Futures Laboratory at Arizona State University.

Andrew Maynard, PhD - ASU Bio
Andrew is a scientist, author, thought leader, and Professor of Advanced Technology Transitions in the ASU School for the Future of Innovation in Society. He is the founder of the ASU Future of Being Human initiative, Director of the ASU Risk Innovation Nexus, and was previously Associate Dean in the ASU College of Global Futures.

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SpudCells: Have Scientists Built Life From Scratch?

Modem Futura

SpudCells: Have Scientists Built Life From Scratch?