Episode cover
04 Sept 2026
18m

Most Replayed Moment: The First Warning Signs Of Insulin Resistance! Check Your Skin For This

Podcast cover

The Diary Of A CEO with Steven Bartlett

High insulin levels accelerate biological aging and promote chronic inflammation by preventing the body from clearing cellular debris. Consuming calories late at night triggers excessive insulin production, which stores energy as fat and hinders metabolic flexibility. Key indicators of insulin resistance include abdominal weight gain, skin tags, darkened skin patches known as acanthosis nigricans, and hair loss on the lower extremities. To combat these effects, Dr. Annette Bosworth advocates for the "Ketone Continuum," a structured approach that transitions individuals from high-frequency eating to time-restricted windows and, eventually, prolonged fasting. By prioritizing fat-forward nutrition and lowering insulin, the body shifts from glucose dependence to ketone production, effectively resetting metabolic health and improving cognitive function. This process restores hormonal communication, particularly in women, while mitigating the long-term health risks associated with chronic metabolic dysfunction.

Outlines

Sign in to continue reading, translating and more.

Open full episode in Podwise