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Y Combinator ยท Business

Y Combinator

All the world is changing around technology and you may contribute a line of code. What will yours be? Subscribe for startup advice, founder stories, and a look inside Y Combinator. What is Y Combinator? We invest $500,000 in every startup and work intensively with the founders for three months. For the life of their company, founders have access to the most powerful community in the world, essential advice, later-stage funding and programs, recruiting resources, and exclusive deals. Visit ycombinator.com to learn more.

Episodes

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The 7 Most Powerful Moats For AI Startups

03 Oct 2025
45m
AI processed

In this episode of The Light Cone, Garry Tan, Jared, Diana, and Harj discuss the concept of "moats" in business, particularly in the context of AI startups, drawing from the book "The Seven Powers" by Hamilton Helmer. They explore how moats, or defensive strategies, are crucial for startups to protect themselves from c...

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Anthropic Head of Pretraining on Scaling Laws, Compute, and the Future of AI

30 Sep 2025
1h 4m
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In this interview podcast, the host speaks with Nick Joseph, Head of Pre-Training at Anthropic, about the basics of pre-training AI models, Anthropic's strategies regarding data, alignment, and infrastructure, and how advances in AI directly result from progress in pre-training. Nick shares his background, including hi...

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Why Now Is The Best Time To Build In Crypto

23 Sep 2025
42m
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Aaron Levie: Why Startups Win In The AI Era

16 Sep 2025
40m
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The discussion centers on the transformative potential of AI in enterprise, contrasting it with the earlier shift to cloud computing. Aaron Levie, CEO of Box, shares his insights on how AI agents can unlock the value of unstructured data, automate tasks, and free up human capital for more strategic initiatives. Levie a...

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The Future of Software Creation with Replit CEO Amjad Masad

12 Sep 2025
42m
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Amjad Massad discusses the future of software development, focusing on Replit's vision of making software creation accessible to everyone through AI agents. He draws parallels between the evolution of computing from mainframes to PCs and the current shift in software engineering from expert-driven to user-friendly. Mas...

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The FDE Playbook for AI Startups with Bob McGrew

08 Sep 2025
50m
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In this episode of The Light Comb podcast, Bob McGrew, an early engineer at PayPal and executive at Palantir and OpenAI, discusses the Forward Deployed Engineer (FDE) model, which originated at Palantir and is now gaining traction among AI agent startups. McGrew explains that an FDE is a technical person who works at t...

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Michael Truell: Building Cursor At 23, Taking On GitHub Copilot & Advice To Engineering Students

03 Sep 2025
27m
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The development of Cursor, an AI-powered code editor, reflects a decade-long journey of technical experimentation and strategic pivots. Founders initially explored diverse applications for AI, including robotic control and mechanical engineering CAD tools, before identifying the transformative potential of AI in softwa...

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OpenAI vs. Deepseek vs. Qwen: Comparing Open Source LLM Architectures

29 Aug 2025
12m
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How This 25-Year-Old Built A $675M Legal AI Startup (With No Legal Experience)

26 Aug 2025
45m
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Anthropic Co-founder: Building Claude Code, Lessons From GPT-3 & LLM System Design

19 Aug 2025
35m
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In this episode of The Light Cone, Garry Tan interviews Tom Brown, co-founder of Anthropic, about his journey from MIT to co-founding a leading AI company. Brown discusses his early experiences at YC startups, his transition into AI research, and his time at OpenAI, including his work on scaling GPT-3. He shares insigh...

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The Sales Playbook For Founders | Startup School

15 Aug 2025
18m
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Dylan Field: Scaling Figma and the Future of Design

08 Aug 2025
40m
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In this interview, Dylan Field, the founder of Figma, discusses the early days of the company, the importance of design in the age of AI, and his perspective on the future of user interfaces. He shares insights on Figma's evolution, from its initial focus on WebGL to becoming a leading design tool, emphasizing the valu...

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The Finance Startup Bringing Agentic AI to Wall Street

31 Jul 2025
46m
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Scaling and the Road to Human-Level AI | Anthropic Co-founder Jared Kaplan

29 Jul 2025
40m
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Jared Kaplan discusses scaling laws in AI, focusing on pre-training and reinforcement learning phases, and how they drive AI progress. He touches on the increasing flexibility and capability of AI models, emphasizing the importance of organizational knowledge, memory, and AI oversight for achieving human-level AI. Kapl...

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Brand Design Tips From Linear Founder Karri Saarinen

25 Jul 2025
43m
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In this episode of Design Review, Karri Saarinen, co-founder and CEO of Linear, joins the host to review startup websites, focusing on branding. Karri emphasizes the importance of authenticity and tailoring the website to the company's current stage, cautioning against creating overly polished sites too early. Using Li...

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Chelsea Finn: Building Robots That Can Do Anything

22 Jul 2025
44m
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Developing general-purpose robots requires shifting from purpose-built models to foundation models that leverage large-scale, diverse data. Physical Intelligence utilizes a "Pi Zero" architecture, which integrates vision-language models with diffusion-based action heads to enable robots to perform complex, long-horizon...

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How Replit Went From $10M to $100M ARR In Just 9 Months

17 Jul 2025
35m
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In this episode of The Breakdown, Amjad Massad, founder and CEO of Replit, discusses the evolution of Replit from a coding education tool to an AI-assisted development platform. Massad shares insights on Replit's shift towards autonomous programming, emphasizing the importance of transactional systems and the ability t...

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Nobel Laureate John Jumper: AI is Revolutionizing Scientific Discovery

15 Jul 2025
27m
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John Jumper discusses his work in AI for science, particularly focusing on the development and impact of AlphaFold, an AI system designed to predict protein structures. He recounts his journey from physics to computational biology and machine learning, emphasizing the importance of research and innovative ideas in crea...

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Aravind Srinivas: Perplexity's Race to Build Agentic Search

11 Jul 2025
43m
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In this interview, Aravind Srinivas, the CEO of Perplexity, discusses the company's origins, its current state, and its future plans to compete with major tech companies like Google and OpenAI. He shares insights on Perplexity's initial focus on natural language to SQL, its evolution into a search and answer engine, an...

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Andrew Ng: Building Faster with AI

10 Jul 2025
43m
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In this Q&A session at Startup School, Andrew Ng from AI Fund shares insights on building AI startups with a focus on speed and execution. He emphasizes the importance of focusing on the application layer of the AI stack and adopting agentic AI workflows. Ng advises startups to work on concrete ideas, rapidly iterate w...

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