This podcast interviews Professor Darren Candow about creatine supplementation. The discussion covers creatine's effects on muscle, bone, and brain health; optimal dosing strategies for different age groups (e.g., higher doses may be beneficial for older adults); and the mechanisms by which creatine works (e.g., cell swelling). Candow notes that creatine's safety profile is excellent, even at higher doses, and that combining creatine with resistance training maximizes its benefits. Listeners gain a comprehensive understanding of creatine's uses and potential benefits, along with practical advice on dosage and consumption methods.