This interview podcast discusses the importance of physical activity, particularly resistance training, in combating the effects of aging. The conversation begins with the guest, Daniel E. Lieberman, reflecting on his own belated commitment to strength training and explaining the detrimental effects of sarcopenia (age-related muscle loss). Lieberman emphasizes that the myth of reduced activity in older age is false, citing humans' unique evolutionary trajectory as grandparents who remained physically active. He highlights a study showing that the benefits of exercise increase with age, significantly reducing mortality rates. Finally, the discussion touches upon the modern convenience-driven lifestyle that discourages physical activity, suggesting that making exercise rewarding is key to overcoming this challenge. A key takeaway is that regular physical activity, especially as we age, is crucial not only for physical health but also for mental well-being and longevity.