This episode of "How I Built This Lab" features Guy Raz and Vicky Tsai (co-founder of Tatcha) answering business questions from callers. The show begins with introductions and sponsor ads, then proceeds to three listener calls, each featuring a founder seeking advice on brand building and marketing strategies for their respective businesses (jewelry, intimate skincare, and gluten-free mug cakes). Vicky and Guy offer practical advice, such as focusing on building a strong community around the brand, leveraging social media for storytelling, and identifying the ideal customer base. Listeners gain insights into overcoming self-doubt as a founder and developing effective marketing strategies for niche products.